Cerebrospinal fluid immunoglobulins in children.

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Cerebrospinal fluid immunoglobulins in children.

Cerebrospinal fluid (CSF) immunoglobulins were measured in 62 normal children, in 9 children with purulent meningitis, and in 10 children with presumptive viral meningitis. The mean values in normal children were IgA 0, IgM 0, and IgG 0.84 +/- 1.4 mg/100 ml (+/- SD). The mean levels of all CSF immunoglobulins were raised in acute bacterial meningitis and were significantly greater than the leve...

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Cerebrospinal fluid immunoglobulins in neurosyphilis.

Using the fluorescent treponemal antibody-absorption (FTA-ABS) test and the solid phase haemadsorption assay (SPHA) Treponema pallidum-specific IgA was found in the cerebrospinal fluid (CSF) of patients with neurosyphilis but not in those with late latent syphilis. The presence of T pallidum-specific IgA in the CSF may inhibit the antitreponemal activity of IgG and thus play some part in the pa...

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Cerebrospinal Fluid Indices in Children with Febrile Convulsion

Background and Objective: Febrile convulsions (FC) are the most common seizure disorders in children. Lumbar puncture should be considered in any case with FC who is suspected to intracranial infections. This study determined white blood cell and polymorphonuclear cell counts, protein and glucose levels in cerebrospinal fluids (CFS) of children that were hospitalized with FC. Methods: In this ...

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Immunoglobulins in cerebrospinal fluid in various neurologic disorders.

We determined the concentrations of immunoglobulins A, G, and M in cerebrospinal fluid of 16 patients suffering from multiple sclerosis, 13 with non-bacterial meningitis, 10 with stroke syndrome, and 13 with epilepsy. The differences in concentrations of immunoglobulins in these groups were remarkable in the patients with multiple sclerosis, meningitis, or stroke syndrome. We propose that the d...

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Cerebrospinal fluid immunoglobulins in cysticercosis of the central nervous system.

Investigation on the behavior of immunoglobulins IGG, IGA and IGM in the CSF, in cases of cysticercosis of the CNS, based on data pertaining to two different series of cases. The first series comprises 30 samples of CSF, and the second one, 5 samples. It was demonstrated that IGG is the one representing the largest contingent. IGG concentration keeps in proportion with the gamma globulin concen...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1979

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.54.12.961